Natural Products and Biomedical Science 04/29/2009
Natcher Conference Center
Bethesda, Maryland
United States
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Natural Products and Biomedical Science

Natcher Auditorium, Natcher Conference Center

04/29/2009 - 04/29/2009

Symposium on natural products: an unparalleled source of drug leads and mechanistic probes

8:00 - 8:15 AM                Introduction
                                       John Schwab, National Institute of General Medical Sciences (NIGMS)
8:15 - 8:45 AM                Perspectives in Industrial Natural Products Research
                                       Frank Petersen, Novartis Institutes for Biomedical Research
8:45 - 9:15 AM                The Microtubule Cytoskeleton as a Target for Natural Products
                                       Susan Band Horwitz, Albert Einstein College of Medicine of Yeshiva University  
9:15 - 9:45 AM                Modified Natural Products as Tubulin-Binding Anticancer Agents
                                       David Kingston, Virginia Polytechnic Institute and State University
9:45 – 10:00 AM             BREAK
10:00 - 10:30 AM            Mining the Information-Rich Content of Natural Products for Biology and Drug Discovery
                                       Daniel Romo, Texas A&M University
10:30 – 11:00 AM           Expanding Natural Product Chemical Diversity With Antibiotic Resistance and Modifying Enzymes
                                       Gerry Wright, McMaster University
11:00 – 11:30 AM           Genome Mining for Novel Lantibiotics
                                       Wilfred van der Donk, University of Illinois at Urbana–Champaign
11:30 – 12:00 PM           The Deep Ocean as a Resource for Medically Important Natural Products
                                       William Fenical, University of California, San Diego
12:00 - 1:00 PM              LUNCH (on your own)
1:00 – 1:30 PM               Insights From Multilateral Symbioses of Insects, Fungi, and Bacteria
                                       Jon Clardy, Harvard Medical School
1:30 – 2:00 PM               Enantioselective Total Synthesis and Absolute Configuration of (-)-Actinophyllic Acid
                                       Larry Overman, University of California, Irvine
2:00 – 2:30 PM               Progress in the Development of Neuroprotective Immunophilin Ligands
                                       Guy Carter, Wyeth Pharmaceuticals
2:30 – 3:00 PM               Chemical Ecology Leads for Drug Discovery
                                       Julia Kubanek, Georgia Institute of Technology
3:00 – 3:15 PM               BREAK
3:15 – 3:45 PM               Natural Products and Synthetic Catalysts
                                       Scott Miller, Yale University
3:45 – 4:15 PM               Targeting Symbiont-Rich Sponges as a Source of Anti-Infectives
                                       Carole Bewley, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
4:15 – 4:45 PM               Drugs for Bad Bugs: Scientific Challenges of Antibacterial Discovery       
                                       David Pompliano, Sanderling Consulting LLC, BioLeap LLC
4:45 – 5:15 PM               Nonribosomal and Ribosomal Biosynthetic Strategies        
                                       Christopher Walsh, Harvard Medical School
5:15 PM                          CONCLUSION